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How long does it take for losartan to get out of your system? Some people who struggle with substance abuse take Losartan to treat their high blood pressure. Losartan's terminal half-life is around two hours, and metabolite half-life is between six to nine hours. It should be out of your system roughly between 10 and 12 hours.
How do beta blockers work in hypertension? Beta blockers, also known as beta -adrenergic blocking agents, are medications that reduce your blood pressure. Beta blockers work by blocking the effects of the hormone epinephrine, also known as adrenaline. Beta blockers cause your heart to beat more slowly and with less force, which lowers blood pressure.

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